Cumming, Jared N.: search on Z-Library

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1

Synthesis and in vitro antimalarial activity of sulfone endoperoxides

Mario D. Bachi, Edward E. Korshin, Poonsakdi Ploypradith, Jared N. Cumming, Suji Xie, Theresa A. Shapiro, Gary H. Posner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 279 KB

english, 1998

2

Recreation of Wöhler’s Synthesis of Urea: An Undergraduate Organic Laboratory Exercise

JAMES D. BATCHELOR, EVERETT E. CARPENTER, GRANT N. HOLDER, CASSANDRA T. EAGLE, JON FIELDER, JARED CUMMINGS

Journal:

The Chemical Educator

Year:

1998

Language:

english

File:

PDF, 351 KB

english, 1998

3

The comparative institutional analysis of energy transitions

Wood, Geoffrey, Finnegan, Jared J, Allen, Maria L, Allen, Matthew M C, Cumming, Douglas, Johan, Sofia, Nicklich, Manuel, Endo, Takahiro, Lim, Sijeong, Tanaka, Seiki

Journal:

Socio-Economic Review

Year:

2019

Language:

english

File:

PDF, 712 KB

english, 2019

4

Modeling a Crowdsourced Definition of Molecular Complexity

Sheridan, Robert P., Zorn, Nicolas, Sherer, Edward C., Campeau, Louis-Charles, Chang, Charlie (Zhenyu), Cumming, Jared, Maddess, Matthew L., Nantermet, Philippe G., Sinz, Christopher J., O’Shea, Paul

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 5.53 MB

english, 2014

5

Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor That Affords Robust CNS Aβ Reduction

Stamford, Andrew W., Scott, Jack D., Li, Sarah W., Babu, Suresh, Tadesse, Dawit, Hunter, Rachael, Wu, Yusheng, Misiaszek, Jeffrey, Cumming, Jared N., Gilbert, Eric J., Huang, Chunli, McKittrick, Brian

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

6

Improved interpretation of amyloid tracer kinetic data through model-based analysis

Stone, Julie, Kleijn, Huub Jan, Bradstreet, Thomas E., Drexel, Melissa, Savage, Mary, Forman, Mark, Spellman, Daniel, Laterza, Omar, Chappell, Derek, Chappell, Gloria, Tanen, Michael, Cumming, Jared,

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 84 KB

english, 2013

7

Antimalarially potent, easily prepared, fluorinated endoperoxides

Gary H. Posner, Xueliang Tao, Jared N. Cumming, Donna Klinedinst, Theresa A. Shapiro

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 219 KB

english, 1996

8

ChemInform Abstract: Structure Based Design of Iminohydantoin BACE1 Inhibitors: Identification of an Orally Available, Centrally Active BACE1 Inhibitor (I).

Jared N. Cumming, et al. et al.

Journal:

Year:

2012

File:

PDF, 21 KB

2012

9

[Advances in Pharmacology] Volume 37 || Antimalarial Activity of Artemisinin (Qinghaosu) and Related Trioxanes: Mechanism (s) of Action

Cumming, Jared N.

Year:

1996

Language:

english

File:

PDF, 2.50 MB

english, 1996

10

Antimalarial 1,2,4-Trioxanes Related to Artemisinin: Rules for Assignment of Relative Stereochemistry in Diversely Substituted Analogs

Ho Oh, Chang, Wang, Dasong, Cumming, Jared N., Posner, Gary H.

Journal:

Spectroscopy Letters

Year:

1997

Language:

english

File:

PDF, 650 KB

english, 1997

11

Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease

Scott, Jack D., Li, Sarah W., Brunskill, Andrew P. J., Chen, Xia, Cox, Kathleen, Cumming, Jared N., Forman, Mark, Gilbert, Eric J., Hodgson, Robert A., Hyde, Lynn A., Jiang, Qin, Iserloh, Ulrich, Kaza

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 3.79 MB

english, 2016

12

Clinical examination of proton pencil beam scanning on a moving anthropomorphic lung phantom

Wang, Peng, Tang, Shikui, Taylor, Paige A., Cummings, David E., Janson, Martin, Traneus, Erik, Sturgeon, Jared D., Lee, Andrew K., Chang, Chang

Journal:

Medical Dosimetry

Year:

2018

Language:

english

File:

PDF, 3.02 MB

english, 2018

13

Paleolimnological assessment of nutrient enrichment on diatom assemblages in a priori defined nitrogen- and phosphorus-limited lakes downwind of the Athabasca Oil Sands, Canada

Laird, Kathleen R., Das, Biplob, Hesjedal, Brittany, Leavitt, Peter R., Mushet, Graham R., Scott, Kenneth A., Simpson, Gavin L., Wissel, Bjorn, Wolfe, Jared, Cumming, Brian F.

Journal:

Journal of Limnology

Year:

2017

Language:

english

File:

PDF, 1.62 MB

english, 2017

14

Further Evidence Supporting the Importance of and the Restrictions on a Carbon-Centered Radical for High Antimalarial Activity of 1,2,4-Trioxanes Like Artemisinin

Posner, Gary H., Wang, Dasong, Cumming, Jared N., Oh, Chang Ho, French, Andrew N., Bodley, Annette L., Shapiro, Theresa A.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 301 KB

english, 1995

15

Researching candidate sites for a carbon storage complex in the Central Appalachian Basin, USA

Cumming, Lydia, Hawkins, Jared, Sminchak, Joel, Valluri, Manoj, Gupta, Neeraj

Journal:

International Journal of Greenhouse Gas Control

Year:

2019

Language:

english

File:

PDF, 3.11 MB

english, 2019

16

Intraoperative prediction of cardiac surgery–associated acute kidney injury using urinary biomarkers of cell cycle arrest

Cummings, Jared J., Shaw, Andrew D., Shi, Jing, Lopez, Marcos G., O'Neal, Jason B., Billings, Frederic T.

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2018

Language:

english

File:

PDF, 717 KB

english, 2018

17

Pharmacological characterization of novel iminoheterocyclic BACE1 inhibitors for the treatment of Alzheimer's disease

Kennedy, Matthew E., Chen, Xia, Kuvelkar, Reshma, Cumming, Jared, Iserloh, Ulrich, McKittrick, Brian, Pan, Janping, Smith, Elizabeth, Sun, Zhong-Yue, Stamford, Andrew, Zhu, Zhaoning, Beyer, Brian, Str

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010

18

Robotic Adrenalectomy for Pheochromocytoma in a Patient with Fontan Physiology

Cummings, Jared J., Siegrist, Kara K., Deegan, Robert J., SolÃ³rzano, Carmen C., Eagle, Susan S.

Journal:

Journal of Cardiothoracic and Vascular Anesthesia

Year:

2020

File:

PDF, 1.07 MB

2020

19

Orally Active Antimalarial 3-Substituted Trioxanes: New Synthetic Methodology and Biological Evaluation

Posner, Gary H., Cumming, Jared N., Woo, Soon-Hyung, Ploypradith, Poonsakdi, Xie, Suji, Shapiro, Theresa A.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 277 KB

english, 1998

20

The Thermal Evolution following a Superburst on an Accreting Neutron Star

Cumming, Andrew, Macbeth, Jared

Journal:

The Astrophysical Journal

Year:

2004

Language:

english

File:

PDF, 96 KB

english, 2004

21

Chronic BACE inhibition dramatically slows the rate of Aß accumulation and the development of amyloid plaques in young TgCRND8 mice

Lynn Hyde, Xia Chen, Lindsay Stahl, Marie Sondey, Jack Scott, Jared Cumming, Andrew Stamford, Eric Parker, Matthew Kennedy

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

22

Chronic BACE inhibition halts further age-related increases in brain Aß and amyloid plaques in aged TgCRND8 mice with established plaques

Lynn Hyde, Cinzia Cantu, Bonnie Werner, Xia Chen, Marie Sondey, Maxine Chen, Blair Weig, Abigail LaShomb, Sherry Lu, Robert Hodgson, Jack Scott, Jared Cumming, Andrew Stamford, Eric Parker, Matthew Ke

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 61 KB

english, 2012

23

Discovery of Cyclic Acylguanidines as Highly Potent and Selective β-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I—Inhibitor Design and Validation ∥ (1)

Zhu, Zhaoning, Sun, Zhong-Yue, Ye, Yuanzan, Voigt, Johannes, Strickland, Corey, Smith, Elizabeth M., Cumming, Jared, Wang, Lingyan, Wong, Jesse, Wang, Yu-Sen, Wyss, Daniel F., Chen, Xia, Kuvelkar, Res

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 3.19 MB

english, 2010

24

Mechanism-based design of simple, symmetrical, easily prepared, potent antimalarial endoperoxides

Gary H. Posner, Dasong Wang, Lluïsa González, Xueliang Tao, Jared N. Cumming, Donna Klinedinst, Theresa A. Shapiro

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 232 KB

english, 1996

25

Effect of a novel BACE inhibitor in the cisterna magna ported conscious rhesus monkey model

Maria Michener, Guoxin Wu, Matthew Kennedy, Jared Cumming, Mandy Dancho, Rachel Korn, Christina Lennox, Izabela Suchecki, David Gilberto, James Hershey, Debra McLoughlin, Zhong-Yue Sun, Zhaoning Zhu,

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 93 KB

english, 2012

26

Health Impact Assessment of Urban Waterway Decisions

Korfmacher, Katrina, Aviles, Katia, Cummings, B.J., Daniell, William, Erdmann, Jared, Garrison, Valerie

Journal:

International Journal of Environmental Research and Public Health

Year:

2014

Language:

english

File:

PDF, 730 KB

english, 2014

27

Piperazine sulfonamide BACE1 inhibitors: Design, synthesis, and in vivo characterization

Jared Cumming, Suresh Babu, Ying Huang, Carolyn Carrol, Xia Chen, Leonard Favreau, William Greenlee, Tao Guo, Matthew Kennedy, Reshma Kuvelkar, Thuy Le, Guoqing Li, Nansie McHugh, Peter Orth, Lynne Oz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 2.34 MB

english, 2010

28

Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor

Jared N. Cumming, Elizabeth M. Smith, Lingyan Wang, Jeffrey Misiaszek, James Durkin, Jianping Pan, Ulrich Iserloh, Yusheng Wu, Zhaoning Zhu, Corey Strickland, Johannes Voigt, Xia Chen, Matthew E. Kenn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 717 KB

english, 2012

29

Evidence for Fe(IV):O in the Molecular Mechanism of Action of the Trioxane Antimalarial Artemisinin

Posner, Gary H., Cumming, Jared N., Ploypradith, Poonsakdi, Oh, Chang Ho

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 315 KB

english, 1995

30

Synthesis and antimalarial activity of heteroatom-containing bicyclic endoperoxides

Gary H. Posner, Lluïsa González, Jared N. Cumming, Donna Klinedinst, Theresa A. Shapiro

Journal:

Year:

1997

Language:

english

File:

PDF, 1.00 MB

english, 1997

31

Isolation and characterization of 11 polymorphic microsatellite loci in collared lizards (Crotaphytus collaris)

DELBERT W. HUTCHISON, JARED L. STRASBURG, JENNIFER A. BRISSON, SHAWN CUMMINGS

Journal:

Molecular Ecology Resources

Year:

2004

Language:

english

File:

PDF, 73 KB

english, 2004

32

Estimating Infrared Radiometric Satellite Sea Surface Temperature Retrieval Cold Biases in the Tropics due to Unscreened Optically Thin Cirrus Clouds

Marquis, Jared W., Bogdanoff, Alec S., Campbell, James R., Cummings, James A., Westphal, Douglas L., Smith, Nathaniel J., Zhang, Jianglong

Journal:

Journal of Atmospheric and Oceanic Technology

Year:

2017

Language:

english

File:

PDF, 1.50 MB

english, 2017

33

Antimalarial sulfone trioxanes

Gary H. Posner, Hardwin O'Dowd, Thomas Caferro, Jared N. Cumming, Poonsakdi Ploypradith, Suji Xie, Theresa A. Shapiro

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 327 KB

english, 1998

34

Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation

Mandal, Mihirbaran, Zhu, Zhaoning, Cumming, Jared N., Liu, Xiaoxiang, Strickland, Corey, Mazzola, Robert D., Caldwell, John P., Leach, Prescott, Grzelak, Michael, Hyde, Lynn, Zhang, Qi, Terracina, Giu

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 678 KB

english, 2012

35

Evidence for the Importance of High-Valent FeO and of a Diketone in the Molecular Mechanism of Action of Antimalarial Trioxane Analogs of Artemisinin

Posner, Gary H., Park, Sheldon B., González, Lluïsa, Wang, Dasong, Cumming, Jared N., Klinedinst, Donna, Shapiro, Theresa A., Bachi, Mario D.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 136 KB

english, 1996

36

Long Type I X‐Ray Bursts and Neutron Star Interior Physics

Cumming, Andrew, Macbeth, Jared, Zand, J. J. M. in ’t, Page, Dany

Journal:

The Astrophysical Journal

Year:

2006

Language:

english

File:

PDF, 683 KB

english, 2006

37

Trioxane dimers have potent antimalarial, antiproliferative and antitumor activities in vitro

Gary H. Posner, Poonsakdi Ploypradith, Whitney Hapangama, Dasong Wang, Jared N. Cumming, Patrick Dolan, Thomas W. Kensler, Donna Klinedinst, Theresa A. Shapiro, Qun Yi Zheng, Christopher K. Murray, Ly

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 940 KB

english, 1997

38

Stereoselective synthesis of 7R-paeonimetaboline-I; Stereoselective route towards paeoniflorigenone

David P. Richardson, Priscilla W. Carr, Jared N. Cumming, Warren G. Harbison, Nina D. Raoof, Michelle S. Sanders, Eliza Shin, Thomas E. Smith, Thomas H. Wintner

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 216 KB

english, 1997

39

Effects of camptothecin, a topoisomerase I inhibitor, on Plasmodium falciparum

Annette L. Bodley, Jared N. Cumming, Theresa A. Shapiro

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 383 KB

english, 1998

40

Design, Synthesis, Derivatization, and Structure−Activity Relationships of Simplified, Tricyclic, 1,2,4-Trioxane Alcohol Analogues of the Antimalarial Artemisinin

Cumming, Jared N., Wang, Dasong, Park, Sheldon B., Shapiro, Theresa A., Posner, Gary H.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 364 KB

english, 1998

41

A Guide to Implementing Enhanced Recovery After Surgery Protocols

Cummings, Jared J., Ehrenfeld, Jesse M., McEvoy, Matthew D.

Journal:

International Anesthesiology Clinics

Year:

2017

Language:

english

File:

PDF, 358 KB

english, 2017

42

Antimalarial Cyclic Peroxy Ketals

Posner, Gary H., O'Dowd, Hardwin, Ploypradith, Poonsakdi, Cumming, Jared N., Xie, Suji, Shapiro, Theresa A.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 78 KB

english, 1998

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